Molecular Inclusion of Large-ring Cyclodextrins
نویسندگان
چکیده
منابع مشابه
Melarsoprol-cyclodextrins inclusion complexes.
Melarsoprol, a water-insoluble drug, is mainly used in the treatment of trypanosomiasis and has demonstrated an in vitro activity on myeloid and lymphoid leukemia derived cell lines. It is marketed as a very poorly tolerated non-aqueous solution (Arsobal). The aim of our work was to develop melarsoprol-cyclodextrin complexes in order to improve the tolerability and the bioavailability of melars...
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Article history: Received on: 26/07/2015 Revised on: 15/08/2015 Accepted on: 09/09/2015 Available online: 27/09/2015 Objective To evaluate the effect of Polyethylene glycol and β-cyclodextrin on the solubility and dissolution of silymarin, a poorly water soluble herbal drug. Methodology Effects of beta cyclodextrins and Polyethylene glycol on solubility of silymarin were evaluated by phase solu...
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Finasteride (FIN) is a Class II candidate of the Biopharmaceutics Classification System (BCS). The lipophilic cavity of cyclodextrins (CyDs) enables it to construct a non-covalent inclusion complex with different insoluble drugs. Only β-cyclodextrin (β-CyD) and hydroxypropyl-β-CyD (HP-β-CyD) have been previously examined with FIN. This study aimed to investigate the consistence of FIN with diff...
متن کاملThe annihilator-inclusion Ideal graph of a commutative ring
Let R be a commutative ring with non-zero identity. The annihilator-inclusion ideal graph of R , denoted by ξR, is a graph whose vertex set is the of allnon-zero proper ideals of $R$ and two distinct vertices $I$ and $J$ are adjacentif and only if either Ann(I) ⊆ J or Ann(J) ⊆ I. In this paper, we investigate the basicproperties of the graph ξR. In particular, we showthat ξR is a connected grap...
متن کاملInvestigation of inclusion complex of epothilone A with cyclodextrins.
The inclusion complexation of Epothilone A with native cyclodextrin (β- or γ-CD) and its derivative hydroxypropyl-β-cyclodextrin (HPβCD) were prepared. Their behavior, characterization, and binding ability were investigated in both solution and the solid state by means of UV-vis, NMR, XRD, DSC and SEM. The results show that the water solubility and solution stability obviously increased in the ...
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ژورنال
عنوان ژورنال: Journal of Applied Glycoscience
سال: 2003
ISSN: 1344-7882,1880-7291
DOI: 10.5458/jag.50.321